Hormones and Alzheimer’s: Is there a Connection?

At Get Well Scottsdale we always ask our clients to ponder this question. “Do we age because we lose our hormones or do we lose our hormones because we age?”  This is an interesting question because as a population we are living longer than ever before, but the question really needs to be about our quality of life as we age. 

Today, everyone seems to know someone that has been diagnosed with, or is suffering from, the effects of Alzheimer’s disease or dementia.  It is a terrible and painful disease for all involved as it destroys brain function and is ultimately fatal.

There are several factors identified and commonly associated with brain abnormalities resulting in Alzheimer’s: (1)

  1. Beta amyloid plaques building up between neurons in the brain;
  2. Neurofibrillary tangles within the neurons (the tangles are composed of the hyper phosphorylated tau protein, which eventually kills the neurons);
  3. Impaired glucose metabolism in the brain (a degree of insulin resistance);
  4. Poor blood circulation to the brain.

A 2013 study in the Journal of Neurology states that women are eight times more likely to get Alzheimer’s than men, and men with low testosterone are three times more likely to suffer from the dementia.  Testosterone is a vaso-dilator, opening blood vessels and increasing blood flow to the brain resulting in more oxygen and nutrition to the brain. 

The connection between metabolism (mitochondria) and Alzheimer’s disease is also being established.  In 2000, Suzanne de la Monte, MD, MPH, was recognized for her innovative research entitled Oxidative Injury and Anti-Oxidant Rescue of the Aging Brain in which she stated that for every Alzheimer’s patient the energy metabolism in the mitochondria was decreased; the amount of enzyme formation was decreased; and the number of mitochondria was decreased.

Thyroid hormones increase the metabolic activities of almost all the tissues of the body – including the number and activity of mitochondria. It also increases the total membrane surface area of the mitochondria in direct proportion to the increased metabolic rate of your body. As the Textbook of Medical Physiology states, “It seems almost to be an obvious deduction that principal function of thyroxin [thyroid hormone] might be simply to increase the number and activity of mitochondria.”

Millions of Americans are experiencing hypothyroid symptoms and are not being treated because their lab work appears to be in the normal ranges. Thyroid dysfunction has been implicated as a cause of reversible cognitive impairment.

In his book Solved: The Riddle of Alzheimer’s Disease, Mark Starr, MD, states the following on how hormones help prevent Alzheimer’s:

  1. Vitamin D3 (a hormone) increases the excretion of beta amyloid from the brain.
  2. Beta amyloid secretion is impaired by both testosterone and estradiol.
  3. Testosterone and estradiol increase alpha secretase activity. Beta secretase is an enzyme that prevents production of beta amyloid. 
  4. Testosterone and estradiol increase neprilysin, an enzyme that degrades beta amyloid.
  5. Testosterone and progesterone inhibit the hyper phosphorylation of tau protein.
  6. Testosterone and estradiol improve brain cell glucose metabolism.
  7. Testosterone and estradiol improve blood flow to the brain.

The latest data that is coming out is showing that 17-Beta-Estradiol may play a role or may be responsible for the actual reversal of Alzheimer’s Disease. More study of course is required, but it is promising and exciting to see that a compound our body makes can actually play a role in protection and reversal of such a debilitating disease.

Self-care and prevention are the keys to optimal health. Paying close attention to how your body feels, and seeking assistance around optimizing your physiology is the key to a long, healthy, and happy life.

Reference: 1) Solved The Riddle of Alzheimer’s Disease by Mark Starr, MD.

What is Lymphatic Therapy?

The most underrated circulatory system in the human body is our lymphatic system. Most health care practitioners never consider the critical role lymph plays in preventing sickness or the

critical role it plays in keeping us healthy.

The lymphatic system is a vital circulatory system, critical to managing the elimination of toxins from our body. The lymphatic system is the primary immune defense and waste eliminator of the body. The lymphatic system contains over 600 “collection” sites called lymph nodes. It has a network of collecting vessels which is even more extensive than the venous system. The lymphatic system is primarily responsible for carrying disease fighting material to cells attacked by germs, transporting the dead germs away and supplying protein rich plasma fluid back to the heart. When this system is congested, your body can become defenseless against attacks by virus, fungus, and bacteria.

Medical research explains the lymphatic system as the primary system used by all immunological support elements (such as macrophages, T-Cells, B-Cells, lymphocytes, etc.) to fight virus, fungus, and bacteria invading the body. It is also composed of over 50% plasma protein and is the major system carrying nutrition rich plasma protein back into our blood.

When the lymphatic system is sluggish, infection fighting material is prevented from destroying germs and cell nourishing elements are prevented from reaching the blood. As a result, germs grow, our blood loses much needed protein, our immune system falters, and infectious diseases march in!

The lymphatic system acts as a reservoir of infection churning out billions of infected immune system cells. When the system becomes overwhelmed, these infected immune cells eventually spill into the blood stream, where they travel to other parts of the body.

Much later, after enduring years of viral proliferation, the immune system begins to falter and infectious disease may take hold. Studies reveals that “up to 10 times as much virus may reside in the lymphatic system as in the blood”.

Most chronic disease problems occur at the junction of lymph vessels called “lymph nodes”. One can feel lymph nodes by pressing under the arms, just below the collarbone or in the crease between the thigh and pelvic area.

When touching these areas, most people will feel small bumps and sometimes pain. The bumps and are symptomatic of blocked lymph nodes.

Blocked lymphatic nodes indicate a breakdown in the mechanical functioning of the lymphatic system.

In men, the inguinal nodes located in the area (crease) of the groin, between the genitals and the thigh are primary channels for letting accumulated lymph (protein and fluid) release from the prostate.

 In women, the auxiliary nodes, located in the arm pit and extend to from the arm pit down toward the breast, are the primary channel for releasing accumulated lymph (protein and fluid) from the breast.

In many cases of prostate, breast and other cancerous situations, these lymph nodes are involved, enlarged and result in a reduced ability to eliminate lymphatic fluid.

What is Lymphatic Therapy using the LBG machine?

The movement of lymphatic fluid has been studied for many years with independent clinical research resulting in very efficient manual methods for restoring the lymphatic system. Modern research, using manual lymphatic drainage techniques in conjunction with a non-invasive technology called the Light Beam Generator (LBG), effects a swift, safe, and natural method of eliminating excess lymphatic fluid.

The LBG machine assists the body to achieve a free flow of protein within the lymph system and to release bonded protein blockages in the interstitium of the connective tissue.

The LBG is a non-invasive technology using extremely low current and negatively charged light photons. This provides compatible frequencies to the blocked area resulting in cells correcting their imbalanced condition and disassociating themselves from the agents responsible for the swelling and blockage.

The LBG machine may assist with rapid movement of waste materials within the cell, and the delivery of the waste materials to the organs responsible for waste management is greatly increased.

With waste materials moving within the body, day to day factors like eating habits, body structure, nutrition, medication and mental health can also be addressed to provide a successful formula for restoring health. Common conditions presenting relief when using the LBG machine are: pain, especially as it involves soft tissue, sciatica, breast conditions, fibrocystic disease, arthritis, bursitis and other conditions where inflammation is involved such as swelling, bruising, and pre/post-op surgical recovery. The LBG machine may increase the healing process by assisting with movement of the lymphatic system.

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Get Well Scottsdale is a holistic healing and wellness center in Scottsdale, Arizona. If you're seeking a holistic doctor with a medical practice focused on disease prevention and healing, schedule with us at Get Well Scottsdale!

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